Dr John B.
15.02.202521:40
Development of anxiety symptoms after receiving the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine: a case series
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1514428/full
"There may be a connection between the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine and the development of anxiety symptoms in patients with pre-existing mental health problems. The potential underlying mechanism warrants further investigation."
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1514428/full
"There may be a connection between the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine and the development of anxiety symptoms in patients with pre-existing mental health problems. The potential underlying mechanism warrants further investigation."
05.01.202507:48
Increased risk of ischemic stroke within 1-42 days after the coadministration of the Pfizer-BioNTech bivalent COVID-19 vaccine and influenza vaccine:
https://publichealth.jmir.org/2024/1/e53807
"The potential association between bivalent vaccination and ischemic stroke in the 1-42–day analysis warrants further investigation among individuals younger than 65 years with influenza vaccine coadministration and prior SARS-CoV-2 infection. Furthermore, the findings on ischemic stroke risk after bivalent COVID-19 vaccination underscore the need to evaluate monovalent COVID-19 vaccine safety during the 2023-2024 season."
https://publichealth.jmir.org/2024/1/e53807
"The potential association between bivalent vaccination and ischemic stroke in the 1-42–day analysis warrants further investigation among individuals younger than 65 years with influenza vaccine coadministration and prior SARS-CoV-2 infection. Furthermore, the findings on ischemic stroke risk after bivalent COVID-19 vaccination underscore the need to evaluate monovalent COVID-19 vaccine safety during the 2023-2024 season."
03.01.202520:30
The SARS-CoV-2 spike protein induces a prolonged vascular inflammatory effect on human endothelial cells -> https://link.springer.com/article/10.1007/s10753-024-02208-x
"... SARS-CoV-2 spike resulted in sustained inflammation, changes in antigen presentation, and coagulation state of the endothelium. The observed prolonged effects beyond the presence of the spike protein suggests possible long-term consequences of SARS-CoV-2 on the endothelium."
"... SARS-CoV-2 spike resulted in sustained inflammation, changes in antigen presentation, and coagulation state of the endothelium. The observed prolonged effects beyond the presence of the spike protein suggests possible long-term consequences of SARS-CoV-2 on the endothelium."
03.01.202511:09
The mRNA COVID-19 vaccine is contaminated with DNA. This has been confirmed by yet another study, which was a high school science project conducted in an FDA laboratory and supervised by FDA scientists -> https://jhss.scholasticahq.com/article/127890-a-rapid-detection-method-of-replication-competent-plasmid-dna-from-covid-19-mrna-vaccines-for-quality-control
- Residual DNA was detected in 6 vials of two different batches of Pfizer COVID-19 mRNA vaccines. - The DNA levels exceeded the safety limits by 6 to 470 times!
The use of mRNA COVID-19 vaccines should be stopped immediately!
- Residual DNA was detected in 6 vials of two different batches of Pfizer COVID-19 mRNA vaccines. - The DNA levels exceeded the safety limits by 6 to 470 times!
The use of mRNA COVID-19 vaccines should be stopped immediately!
23.12.202407:13
Optic neuritis & short-segment myelitis following ChAdOx1 adenovirus COVID-19 vaccination: https://journals.lww.com/neur/fulltext/2024/11000/optic_neuritis_and_short_segment_myelitis.28.aspx
- "Magnetic resonance imaging of the brain showed T2/FLAIR hyperintensity of the right optic nerve. The middle portion of the right optic nerve showed mild enhancement."
- "MRI of the spinal cord demonstrated a short-segment T2/FLAIR hyperintensity in the cervicothoracic region" (-> small vessel spinal cord strokes)
- "Magnetic resonance imaging of the brain showed T2/FLAIR hyperintensity of the right optic nerve. The middle portion of the right optic nerve showed mild enhancement."
- "MRI of the spinal cord demonstrated a short-segment T2/FLAIR hyperintensity in the cervicothoracic region" (-> small vessel spinal cord strokes)
01.12.202419:31
(7/n)
Systematic studies are now needed to investigate these large clots using ThT-based fluorescence microscopy and, ideally, staining of NETs, as well as quantification of the amyloid fibrin microclot concentration (and size distribution) in plasma.
This would actually be a topic for a @Nature or @ScienceMagazine paper – which research group dares to tackle this hot and difficult topic?
For an earlier analysis of these clots, see my older post: https://x.com/DrJohnB2/status/1807188321665212922
Systematic studies are now needed to investigate these large clots using ThT-based fluorescence microscopy and, ideally, staining of NETs, as well as quantification of the amyloid fibrin microclot concentration (and size distribution) in plasma.
This would actually be a topic for a @Nature or @ScienceMagazine paper – which research group dares to tackle this hot and difficult topic?
For an earlier analysis of these clots, see my older post: https://x.com/DrJohnB2/status/1807188321665212922
30.01.202509:41
Will we all soon be indirectly vaccinated by eating meat?
In France, a self-amplifying mRNA vaccine is now being used in the factory farming of ducks.
Helene Banoun (@BanounHelene) has published an important article on the subject: https://tinyurl.com/285hwx6u
- "The CEVA vaccine is a self-amplifying mRNA encoding H5 of H5N8 coated in ferric nanoparticles, and contains squalene (suspected of toxicity in humans)."
- "When ducks are vaccinated with CEVA's self-amplifying mRNA product, it must be emphasized that no tests have been carried out on the ability of this gene product to be transmitted to the duck meat consumer."
In France, a self-amplifying mRNA vaccine is now being used in the factory farming of ducks.
Helene Banoun (@BanounHelene) has published an important article on the subject: https://tinyurl.com/285hwx6u
- "The CEVA vaccine is a self-amplifying mRNA encoding H5 of H5N8 coated in ferric nanoparticles, and contains squalene (suspected of toxicity in humans)."
- "When ducks are vaccinated with CEVA's self-amplifying mRNA product, it must be emphasized that no tests have been carried out on the ability of this gene product to be transmitted to the duck meat consumer."
05.01.202507:32
COVID-19 mRNA vaccines are associated with higher incidence of adverse events compared to other vaccines
-> https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1336906/full
-> https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1336906/full
03.01.202520:13
Kawasaki disease in a 2-month-old boy 5 days after receiving the DTwP-HepB-Hib (5-in-1) vaccine
-> https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-024-04987-1
Kawasaki disease: an acute inflammatory disorder primarily affecting medium-sized blood vessels.
"Early diagnosis and timely intervention are essential to prevent severe complications, such as coronary artery aneurysms and possible mortality. It underscores the need for heightened awareness and vigilance among healthcare providers in similar clinical scenarios."
-> https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-024-04987-1
Kawasaki disease: an acute inflammatory disorder primarily affecting medium-sized blood vessels.
"Early diagnosis and timely intervention are essential to prevent severe complications, such as coronary artery aneurysms and possible mortality. It underscores the need for heightened awareness and vigilance among healthcare providers in similar clinical scenarios."
23.12.202407:58
New study
Changing epidemiology of myocarditis in Australia: A population-nased cohort study:
https://www.mdpi.com/2077-0383/13/23/7111
Analyzed data: 2001-2022
"There was an inflexion point in 2021 during which the growth rate in the incidence of myocarditis accelerated. By 2022, the incidence of myocarditis was about 8 cases per-100,000 with no sign of slowing."
"The current study underlines the rising incidence of myocarditis, especially post-pandemic."
I am wondering about this sharp increase in cases of myocarditis. What could be the reason? Any ideas? ...
Changing epidemiology of myocarditis in Australia: A population-nased cohort study:
https://www.mdpi.com/2077-0383/13/23/7111
Analyzed data: 2001-2022
"There was an inflexion point in 2021 during which the growth rate in the incidence of myocarditis accelerated. By 2022, the incidence of myocarditis was about 8 cases per-100,000 with no sign of slowing."
"The current study underlines the rising incidence of myocarditis, especially post-pandemic."
I am wondering about this sharp increase in cases of myocarditis. What could be the reason? Any ideas? ...
23.12.202407:05
https://link.springer.com/article/10.1007/s12026-024-09553-x#Sec7
"The vaccines imposed severe potential health side effects such as clotting or obstruction of blood vessels termed arterial or venous thrombosis, autoimmune damage of nerve cells (Guillain-Barré syndrome; GBS), intense activation of coagulation system (vaccine-induced thrombotic thrombocytopenia), acute ischemic stroke (AIS) and cerebral venous sinus thrombosis (CVST), myocarditis, pericarditis, and glomerular disease."
- "It is essential to continue rigorous follow-up and surveillance studies to monitor vaccine safety and identify potential risks, particularly in immunocompromised individuals, those with comorbidities, and other vulnerable populations."
- "Long-term data on vaccine interactions, effects during pregnancy, and implications for individuals with autoimmune or inflammatory conditions are still needed."
"The vaccines imposed severe potential health side effects such as clotting or obstruction of blood vessels termed arterial or venous thrombosis, autoimmune damage of nerve cells (Guillain-Barré syndrome; GBS), intense activation of coagulation system (vaccine-induced thrombotic thrombocytopenia), acute ischemic stroke (AIS) and cerebral venous sinus thrombosis (CVST), myocarditis, pericarditis, and glomerular disease."
- "It is essential to continue rigorous follow-up and surveillance studies to monitor vaccine safety and identify potential risks, particularly in immunocompromised individuals, those with comorbidities, and other vulnerable populations."
- "Long-term data on vaccine interactions, effects during pregnancy, and implications for individuals with autoimmune or inflammatory conditions are still needed."
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01.12.202419:30
(6/n)
The fact that these clots stain positive for ThT is not good news, as it indicates that these clots are special and cannot be easily dissolved by the body through fibrolysis.
Presumably, these clots are also full of neutrophil extracellular traps (NETs), as has already been shown for amyloid-fibrin microclots (which are probably the smaller form of these macroclots) [1]:
[1] https://www.researchsquare.com/article/rs-4666650/v1
The fact that these clots stain positive for ThT is not good news, as it indicates that these clots are special and cannot be easily dissolved by the body through fibrolysis.
Presumably, these clots are also full of neutrophil extracellular traps (NETs), as has already been shown for amyloid-fibrin microclots (which are probably the smaller form of these macroclots) [1]:
[1] https://www.researchsquare.com/article/rs-4666650/v1
05.01.202521:19
05.01.202507:27
"Activation and differentiation of T cells into effector cells are thought to rely on three signals received from antigen-presenting cells (APCs), such as dendritic cells (DCs). The first signal is in the form of peptide-MHC, the second signal is membrane-bound co-stimulation, and the third signal is in the form of soluble cytokines. If the T cells receive the third signal before the first one, it is called out-of-sequence stimulation, which can lead to the T cells’ death or render them anergic and non-responsive (136, 137). Exposure to mRNA-LNP or LNP leads to a rapid release of inflammatory cytokines (12), including type I interferons (7) that are known to induce out-of-sequence stimulation, which likely exposes the adaptive immune cells, including the T cells, to an inflammatory environment before the mRNA is translated into protein and presented on DCs. Thus, with a high likelihood, one of the potential flaws of the mRNA-LNP platform, unlike the old-school vaccines where the antigen presentation and inflammation coincide, is that it exposes the adaptive immune cells to an out-of-sequence stimulation, which might worsen upon further exposure."
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1336906/full
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1336906/full
03.01.202517:09
Bullous pemphigoid (BP) (an autoimmune blistering disease) 4 days after vaccination (DPT, polio, hepatitis B, Haemophilus influenzae type b, whooping cough, rotavirus, and pneumococcal vaccines) and after a 7-day flucloxacillin course
-> https://www.cureus.com/articles/322380-bullous-pemphigoid-onset-following-vaccination-in-infancy-a-case-report#!/
Case of a 4 month-old infant.
"Future research should focus on analysing the routes through which vaccinations modulate the immune system since these may increase the risk of autoimmune diseases ..."
-> https://www.cureus.com/articles/322380-bullous-pemphigoid-onset-following-vaccination-in-infancy-a-case-report#!/
Case of a 4 month-old infant.
"Future research should focus on analysing the routes through which vaccinations modulate the immune system since these may increase the risk of autoimmune diseases ..."
23.12.202407:40
SARS-CoV-2 vaccine-associated liver injury (SVALI):
https://onlinelibrary.wiley.com/doi/10.1111/liv.16209
- "The heterogeneous clinical entity of acute liver injury linked to SARS-CoV-2 vaccines includes patients requiring long-term immunosuppression, similarly to autoimmune hepatitis, and patients with self-limiting liver damage, possibly representing a unique form of autoimmune-like hepatitis, which we suggest being referred to as SARS-CoV-2 vaccine-associated liver injury (SVALI)."
- "Further studies are needed to investigate the pathogenic mechanisms related to the immune response to the spike viral protein in the liver."
https://onlinelibrary.wiley.com/doi/10.1111/liv.16209
- "The heterogeneous clinical entity of acute liver injury linked to SARS-CoV-2 vaccines includes patients requiring long-term immunosuppression, similarly to autoimmune hepatitis, and patients with self-limiting liver damage, possibly representing a unique form of autoimmune-like hepatitis, which we suggest being referred to as SARS-CoV-2 vaccine-associated liver injury (SVALI)."
- "Further studies are needed to investigate the pathogenic mechanisms related to the immune response to the spike viral protein in the liver."
23.12.202406:59
Syncopes, paresis & loss of vision after COVID-19 mRNA-based vaccination & SARS-CoV-2 infection: https://link.springer.com/article/10.1007/s15010-024-02439-y
- "6 h after vaccination, the patient developed severe cephalgia & dizziness lasting for several days"
- "Spontaneous syncope occurred 20–30 times over the following 2 weeks. Even though the syncopes disappeared, the patient continued to observe irregular heartbeats. ... he reported new onset of fatigue, brain fog, acral paresthesia, paresis of forearm extensors and Mm. quadriceps femoris, disseminated fasciculations & urticaria in the weeks following the vaccination"
- "143 days after vaccination, the patient suffered a PCR confirmed SARS-CoV-2 infection, and the symptoms experienced after vaccination exacerbated"
- "The details on the mechanisms underlying adverse side effects caused by mRNA-based vaccines remain unclear"
- "Further mechanistic research assessing the pathologies that may trigger mRNA vaccine-associated symptoms are urgently needed"
- "6 h after vaccination, the patient developed severe cephalgia & dizziness lasting for several days"
- "Spontaneous syncope occurred 20–30 times over the following 2 weeks. Even though the syncopes disappeared, the patient continued to observe irregular heartbeats. ... he reported new onset of fatigue, brain fog, acral paresthesia, paresis of forearm extensors and Mm. quadriceps femoris, disseminated fasciculations & urticaria in the weeks following the vaccination"
- "143 days after vaccination, the patient suffered a PCR confirmed SARS-CoV-2 infection, and the symptoms experienced after vaccination exacerbated"
- "The details on the mechanisms underlying adverse side effects caused by mRNA-based vaccines remain unclear"
- "Further mechanistic research assessing the pathologies that may trigger mRNA vaccine-associated symptoms are urgently needed"
01.12.202419:30
(5/n)
05.01.202508:58
Neuro-Sjögren's syndrome (SS) in a 34-year-old woman 9 months after she received her third dose of COVID-19 vaccination -> https://www.cureus.com/articles/287454-new-onset-of-neuro-sjgrens-syndrome-nine-months-after-the-third-covid-19-vaccine-dose-a-case-report#!/
SS: an autoimmune chronic inflammatory disease causing peripheral nerve system and central nervous system issues.
- "The present case report is about a 34-year-old woman who presented with progressive numbness, difficulty in walking, and blurred vision following the COVID-19 vaccine booster, but she never had COVID-19 or any infection."
- "This case highlights the need for increased vigilance and research into vaccine-induced autoimmunity."
SS: an autoimmune chronic inflammatory disease causing peripheral nerve system and central nervous system issues.
- "The present case report is about a 34-year-old woman who presented with progressive numbness, difficulty in walking, and blurred vision following the COVID-19 vaccine booster, but she never had COVID-19 or any infection."
- "This case highlights the need for increased vigilance and research into vaccine-induced autoimmunity."
05.01.202507:27
Another mechanism by which the COVID-19 vaccines can lead to a systemic weakening of the immune system: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1336906/full
An "out-of-sequence stimulation" is triggered.
- "... these data suggest that the inflammatory environment created by the LNPs is detrimental to naïve T cells."
"... the observed changes were likely systemic since the direct draining organs, the skin-draining lymph nodes, and the distant spleen showed similar trends."
"These data align with our previous findings that exposure to mRNA-LNP or LNP leads to systemic inhibition of adaptive immune responses."
"... it exposes the adaptive immune cells to an out-of-sequence stimulation, which might worsen upon further exposure."
An "out-of-sequence stimulation" is triggered.
- "... these data suggest that the inflammatory environment created by the LNPs is detrimental to naïve T cells."
"... the observed changes were likely systemic since the direct draining organs, the skin-draining lymph nodes, and the distant spleen showed similar trends."
"These data align with our previous findings that exposure to mRNA-LNP or LNP leads to systemic inhibition of adaptive immune responses."
"... it exposes the adaptive immune cells to an out-of-sequence stimulation, which might worsen upon further exposure."
03.01.202516:15
Case of a 19 year-old woman experiencing significant breast hypertrophy starting 1 week after receiving the Pfizer COVID-19 vaccine in September 2022.
"The patient initially reported tingling paresthesia in her breasts, followed by sudden bilateral growth which worsened after receiving the second vaccine dose. Over 6 months, her breast size increased from a B cup to a triple G."
-> https://journals.lww.com/prsgo/fulltext/2024/12000/the__pfizer_boob_job___a_case_of_unexplained.52.aspx
"The association between the COVID-19 vaccine, PASH, and breast hypertrophy warrants further investigation to comprehend the spectrum of reactions to the vaccine."
"The patient initially reported tingling paresthesia in her breasts, followed by sudden bilateral growth which worsened after receiving the second vaccine dose. Over 6 months, her breast size increased from a B cup to a triple G."
-> https://journals.lww.com/prsgo/fulltext/2024/12000/the__pfizer_boob_job___a_case_of_unexplained.52.aspx
"The association between the COVID-19 vaccine, PASH, and breast hypertrophy warrants further investigation to comprehend the spectrum of reactions to the vaccine."
23.12.202407:31
Kounis syndrome following COVID-19 vaccination: https://www.tandfonline.com/doi/10.1080/21645515.2024.2365496?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed#abstract
Kounis syndrome: "an acute coronary syndrome triggered by allergic mediators that induce coronary vasoconstriction and thrombosis, leading to further myocardial damage and anaphylactic shock."
- "Most patients developed clinical manifestations associated with Kounis syndrome within 2 hours of vaccination and progressed rapidly."
Kounis syndrome: "an acute coronary syndrome triggered by allergic mediators that induce coronary vasoconstriction and thrombosis, leading to further myocardial damage and anaphylactic shock."
- "Most patients developed clinical manifestations associated with Kounis syndrome within 2 hours of vaccination and progressed rapidly."
01.12.202420:52
In Germany, there is now a laboratory where you can get tested to see if you have components of the mRNA vaccine in your body (blood, tissue samples, etc.).
-> https://inmodia.de/en/
The Institute of Molecular Diagnostics (INMODIA GmbH) offers detection of:
- Spike protein
- ‘Vaccine mRNA’ (modRNA)
- Contaminating DNA (plasmid DNA)
These components can be detected in the following sample materials:
- Tissue samples (biopsy or autopsy materials, fixed or unfixed)
- Blood plasma
- Cerebrospinal fluid
- Immune cells from whole blood or cerebrospinal fluid
It's great that a service like this is now available!
I expect that many more such laboratories will be opened worldwide in the near future, or that existing laboratories will start offering these services...
-> https://inmodia.de/en/
The Institute of Molecular Diagnostics (INMODIA GmbH) offers detection of:
- Spike protein
- ‘Vaccine mRNA’ (modRNA)
- Contaminating DNA (plasmid DNA)
These components can be detected in the following sample materials:
- Tissue samples (biopsy or autopsy materials, fixed or unfixed)
- Blood plasma
- Cerebrospinal fluid
- Immune cells from whole blood or cerebrospinal fluid
It's great that a service like this is now available!
I expect that many more such laboratories will be opened worldwide in the near future, or that existing laboratories will start offering these services...
01.12.202419:29
(4/n)
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